diff --git a/src/core/display/DisplayObject.js b/src/core/display/DisplayObject.js
index 4e6c77d..f5d615c 100644
--- a/src/core/display/DisplayObject.js
+++ b/src/core/display/DisplayObject.js
@@ -113,6 +113,15 @@
          * @private
          */
         this._mask = null;
+
+        /**
+         * If the object has been destroyed via destroy(). If true, it should not be used.
+         *
+         * @member {boolean}
+         * @private
+         * @readonly
+         */
+        this._destroyed = false;
     }
 
     /**
@@ -403,6 +412,8 @@
 
         this.interactive = false;
         this.interactiveChildren = false;
+
+        this._destroyed = true;
     }
 
     /**

diff --git a/src/core/display/DisplayObject.js b/src/core/display/DisplayObject.js
index 4e6c77d..f5d615c 100644
--- a/src/core/display/DisplayObject.js
+++ b/src/core/display/DisplayObject.js
@@ -113,6 +113,15 @@
          * @private
          */
         this._mask = null;
+
+        /**
+         * If the object has been destroyed via destroy(). If true, it should not be used.
+         *
+         * @member {boolean}
+         * @private
+         * @readonly
+         */
+        this._destroyed = false;
     }
 
     /**
@@ -403,6 +412,8 @@
 
         this.interactive = false;
         this.interactiveChildren = false;
+
+        this._destroyed = true;
     }
 
     /**
diff --git a/src/core/textures/BaseTexture.js b/src/core/textures/BaseTexture.js
index aeccf39..bbee141 100644
--- a/src/core/textures/BaseTexture.js
+++ b/src/core/textures/BaseTexture.js
@@ -203,6 +203,15 @@
         }
 
         /**
+         * If the object has been destroyed via destroy(). If true, it should not be used.
+         *
+         * @member {boolean}
+         * @private
+         * @readonly
+         */
+        this._destroyed = false;
+
+        /**
          * Fired when a not-immediately-available source finishes loading.
          *
          * @protected
@@ -598,6 +607,8 @@
         this.source = null;
 
         this.dispose();
+
+        this._destroyed = true;
     }
 
     /**

diff --git a/src/core/display/DisplayObject.js b/src/core/display/DisplayObject.js
index 4e6c77d..f5d615c 100644
--- a/src/core/display/DisplayObject.js
+++ b/src/core/display/DisplayObject.js
@@ -113,6 +113,15 @@
          * @private
          */
         this._mask = null;
+
+        /**
+         * If the object has been destroyed via destroy(). If true, it should not be used.
+         *
+         * @member {boolean}
+         * @private
+         * @readonly
+         */
+        this._destroyed = false;
     }
 
     /**
@@ -403,6 +412,8 @@
 
         this.interactive = false;
         this.interactiveChildren = false;
+
+        this._destroyed = true;
     }
 
     /**
diff --git a/src/core/textures/BaseTexture.js b/src/core/textures/BaseTexture.js
index aeccf39..bbee141 100644
--- a/src/core/textures/BaseTexture.js
+++ b/src/core/textures/BaseTexture.js
@@ -203,6 +203,15 @@
         }
 
         /**
+         * If the object has been destroyed via destroy(). If true, it should not be used.
+         *
+         * @member {boolean}
+         * @private
+         * @readonly
+         */
+        this._destroyed = false;
+
+        /**
          * Fired when a not-immediately-available source finishes loading.
          *
          * @protected
@@ -598,6 +607,8 @@
         this.source = null;
 
         this.dispose();
+
+        this._destroyed = true;
     }
 
     /**
diff --git a/src/prepare/BasePrepare.js b/src/prepare/BasePrepare.js
index 09eb5e5..a4aae2f 100644
--- a/src/prepare/BasePrepare.js
+++ b/src/prepare/BasePrepare.js
@@ -172,13 +172,16 @@
             const item = this.queue[0];
             let uploaded = false;
 
-            for (let i = 0, len = this.uploadHooks.length; i < len; i++)
+            if (item && !item._destroyed)
             {
-                if (this.uploadHooks[i](this.uploadHookHelper, item))
+                for (let i = 0, len = this.uploadHooks.length; i < len; i++)
                 {
-                    this.queue.shift();
-                    uploaded = true;
-                    break;
+                    if (this.uploadHooks[i](this.uploadHookHelper, item))
+                    {
+                        this.queue.shift();
+                        uploaded = true;
+                        break;
+                    }
                 }
             }
 

diff --git a/src/core/display/DisplayObject.js b/src/core/display/DisplayObject.js
index 4e6c77d..f5d615c 100644
--- a/src/core/display/DisplayObject.js
+++ b/src/core/display/DisplayObject.js
@@ -113,6 +113,15 @@
          * @private
          */
         this._mask = null;
+
+        /**
+         * If the object has been destroyed via destroy(). If true, it should not be used.
+         *
+         * @member {boolean}
+         * @private
+         * @readonly
+         */
+        this._destroyed = false;
     }
 
     /**
@@ -403,6 +412,8 @@
 
         this.interactive = false;
         this.interactiveChildren = false;
+
+        this._destroyed = true;
     }
 
     /**
diff --git a/src/core/textures/BaseTexture.js b/src/core/textures/BaseTexture.js
index aeccf39..bbee141 100644
--- a/src/core/textures/BaseTexture.js
+++ b/src/core/textures/BaseTexture.js
@@ -203,6 +203,15 @@
         }
 
         /**
+         * If the object has been destroyed via destroy(). If true, it should not be used.
+         *
+         * @member {boolean}
+         * @private
+         * @readonly
+         */
+        this._destroyed = false;
+
+        /**
          * Fired when a not-immediately-available source finishes loading.
          *
          * @protected
@@ -598,6 +607,8 @@
         this.source = null;
 
         this.dispose();
+
+        this._destroyed = true;
     }
 
     /**
diff --git a/src/prepare/BasePrepare.js b/src/prepare/BasePrepare.js
index 09eb5e5..a4aae2f 100644
--- a/src/prepare/BasePrepare.js
+++ b/src/prepare/BasePrepare.js
@@ -172,13 +172,16 @@
             const item = this.queue[0];
             let uploaded = false;
 
-            for (let i = 0, len = this.uploadHooks.length; i < len; i++)
+            if (item && !item._destroyed)
             {
-                if (this.uploadHooks[i](this.uploadHookHelper, item))
+                for (let i = 0, len = this.uploadHooks.length; i < len; i++)
                 {
-                    this.queue.shift();
-                    uploaded = true;
-                    break;
+                    if (this.uploadHooks[i](this.uploadHookHelper, item))
+                    {
+                        this.queue.shift();
+                        uploaded = true;
+                        break;
+                    }
                 }
             }
 
diff --git a/test/prepare/BasePrepare.js b/test/prepare/BasePrepare.js
index 03cf2fa..3cfa476 100644
--- a/test/prepare/BasePrepare.js
+++ b/test/prepare/BasePrepare.js
@@ -121,6 +121,40 @@
         prep.destroy();
     });
 
+    it('should remove destroyed items from queue', function ()
+    {
+        const prep = new PIXI.prepare.BasePrepare();
+
+        const addHook = sinon.spy(function (item, queue)
+        {
+            queue.push(item);
+
+            return true;
+        });
+        const uploadHook = sinon.spy(function ()
+        {
+            return false;
+        });
+        const complete = sinon.spy(function () { /* empty */ });
+
+        prep.register(addHook, uploadHook);
+        const item = {};
+
+        prep.upload(item, complete);
+
+        expect(prep.queue).to.have.lengthOf(1);
+
+        item._destroyed = true;
+        prep.prepareItems();
+
+        expect(prep.queue).to.be.empty;
+        expect(addHook.calledOnce).to.be.true;
+        expect(uploadHook.called).to.be.false;
+        expect(complete.calledOnce).to.be.true;
+
+        prep.destroy();
+    });
+
     it('should attach to SharedTicker', function (done)
     {
         const prep = new PIXI.prepare.BasePrepare();